Therapeutic application of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression

Repetitive, transcranial magnetic stimulation (rTMS) is one of the treatments of choice, especially in the treatment of therapy-resistant depression. The rTMS therapy options become the preferred option where drug treatment does not adequately address the problem or if the drug treatment has undesirable side effects. It is also a treatment of choice when there are contraindications for drug treatment, the drug is rejected by the patient, or if patients do not respond appropriately to psychotherapeutic measures.

Treatments with rTMS in combination with methods such as pharmacotherapy and psychotherapy is also possible. Magnetic stimulation >> is painless and well-tolerated by patients with depression, and it does not have significant side effects.

rTMS in treating therapy-resistant depression

Repetitive transcranial magnetic stimulation has a high level of evidence in treating therapy-resistant depression.

In order to accurately determine the individual stimulation intensity required and the ideal locus of stimulation for a particular patient, a low level magnetic pulse is generated using a magnetic coil. The stimulation pulse is applied to the patient's head, and the coil induces an electrical stimulation pulse in the cortical area, resulting in a depolarisation of cortical neurons. Through various, high-frequency stimulation protocols in depression treatment, the cortical activity is modulated and normalized through targeted stimulation of the dorsolateral prefrontal cortex (DLPFC). A number of studies and meta-studies demonstrate the effectiveness, especially in the treatment of depression.

rTMS is used as a therapeutic approach for a variety of neuro-psychiatric disorders

In addition to depression, rTMS is considered to be a potential treatment option for a variety of additional neuro-psychiatric indications. These include tinnitus, mania, obsessive-compulsive disorder, schizophrenia, conversion disorders and panic disorders. In addition, the therapeutic effectiveness of rTMS, the technique is being studied in rehabilitation medicine, addictions, eating disorders, Morbus Parkinson, Tourette’s syndrome, writer’s cramp, dystonia, phantom pain, stuttering, etc.

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